Primary Alveolar Soft Part Sarcoma of Chest Wall: A Case Report and Review of the Literature

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MedGenMed. 2006; 8(3): 2.

Published online 2006 Jul 5

Review of the Literature


Farhad Zamani, MD, Assistant Professor of Gastroenterology, Mosadegh Jabbari, MD, Assisstant Professor of Nephrology, Seyed Maysam Alimohamadi, MD, Research Fellow, Ramin Shakeri, MD, Research Fellow, Zohreh Rostami, MD, Internist, Behnoush Abedi, MD, Pathologist, Mahshid Hormazdi, MD, Associate Professor of Pathology, and Reza Malekzadeh, MD, Professor of Medicine

Introduction

Alveolar soft part sarcoma (ASPS), also called alveolar soft-tissue sarcoma (ASTS), is a rare malignant soft-tissue neoplasm, which was first described by Christopherson and colleagues[1] in 1952. Its prevalence is less than 1% of all primary soft-tissue sarcomas.[2] The histogenesis of ASPS is not clear; however, a myogenic phenotype and skeletal muscle differentiation are favored.[3,4] It is more common in adolescents and young adults, especially in those who are 15-35 years old; occurs more commonly in women; and is rarely seen in children.[5]

ASPS most commonly originates from the deep tissues of the proximal parts of the extremities, especially the lower limbs,[5] and shows right-sided laterality, as described by Fassbender.[6] In children the primary site is in the head and neck. It usually appears as a painless mass in the thigh or leg, but it may initially appear from other sites of the body. Regardless of its indolent growth pattern, the ultimate prognosis remains poor because of early metastatic spread to the lungs, bone, brain, and lymph nodes in order of frequency.[7]




https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781299/

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My primary tumore was in the chest wall. It was removed by a surgeon at St. Jude's Children Hospital in 2007.