Cediranib for Metastatic Alveolar Soft Part Sarcoma
http://jco.ascopubs.org/content/31/18/2296.full
Conclusion:
In this largest prospective trial to date of systemic therapy for metastatic ASPS, we observed that cediranib has substantial single-agent activity, producing an ORR of 35% and a disease control rate of 84% at 24 weeks. On the basis of these results, an open-label, multicenter, randomized phase II registration trial is currently being conducted for patients with metastatic ASPS comparing cediranib with another VEGFR inhibitor, sunitinib.
Full text is avail. at the link.
Interim results of the cediranib trial at NCI
One of the most promising trials currently open.
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