iCureASPS is Marking 20 Years of Activity

The first weekend of August 2023 is marking 20 years of iCureASPS efforts to find a cure for Alveolar Soft Part Sarcoma (ASPS). This weekend “Team ASPS” will ride for the 20^th time at the PMC bike ride. Please donate and support our efforts to find a cure for ASPS.

Through Saturday and Sunday, August 5^th, and 6^th 2023, “Team ASPS” will ride at the Pan-Massachusetts Challenge (PMC). The PMC is a bike-a-thon that crosses Massachusetts to raise money for cancer research and clinical trials at the Dana-Farber Cancer Institute in Boston. With the help of our donors over the past 20 years, we have raised over $600,000 exclusively for ASPS research.

In 2005, following our second ride with “Team ASPS”, we were able to initiate the first ever human ASPS clinical trial, the Cancer Vaccine clinical Trial (GVAX) developed by Dr. Glenn Dranoff at the Dana Farber Cancer Institute. This sparked additional clinical trials including ARQ197, Cediranib, anlotinib, Axitinib and Pembrolizumab. Last year marked a major accomplishment for ASPS patients, when TECENTRIQ (atezolizumab) was approved by the FDA as the first ASPS drug.

Your donation will help us continue collaborative research on ASPS at the Dana Farber Cancer Institute and initiate a new human clinical trial for ASPS.

Our current research efforts at Dana Farber and University of Massachusetts Memorial Children’s Medical Center are conducted by Dr. Matthew Hemming, Dr. Ewa Sicinska and Dr. George Demetri. This year we continue to conduct a genetic CRISPR screen using ASPS cell lines to learn about the biology of ASPS and identify specific ASPS targets for therapy. Just recently, Dr. Hemming and Dr. Sicinska submitted a scientific manuscript for publication that describes their recent preclinical studies on ASPS.

Cure Alveolar Soft Part Sarcoma International (iCureASPS) organization aims to bring together ASPS patients, families and friends from all over the world with a shared interest to find a cure. Our interactive Forum enables ASPS patients to find information, share their experiences, and receive group support from the ASPS community. It is through this forum that patients around the world can make better decisions regarding their ASPS treatments.

Show your support and use the PMC rider page to make your donation: https://profile.pmc.org/YL0002

Once you are on my page, click on the right side: “DONATE TO MY RIDE”, or on the left side: “DONATE BY VENMO”.

Your donation is a fully tax deductible. The PMC tax ID is: 04-2746912

Thank you for your support!

Best Wishes,

Yosef Landesman

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Yosef Landesman, Ph.D.

President & Cancer Research Director

Cure Alveolar Soft Part Sarcoma International (iCureASPS)

e-mail: landesmany@yahoo.com