New successful trial: AZD2171

[Paul]

Hello everyone,

I may not be well known by some on this board, and maybe forgotten by others, as it has been a long time since I have posted here. I would like to fill everyone in on the success I have been fortuunate enough to have with this new clinical trial.

I am based in London at the Royal Marsden Hospital (a cancer specialising hospital) under Dr. Ian Judson. I have been taking part in the trial for over six months now, and have had positive results throughout.

RESULTS:
I have had three scans since I first began on the trial, at 8 weeks, 16 weeks and 32 weeks (I think these are the correct times, I may be slightly wrong)!

8 weeks: No new tumor growth, a good number of tumors in my lungs and one in the muscle tissue of my back had reduced in size by 10% or more. I have 3 tumors in my brain the largest at that time was 15mm. All brain tumors either showed stability or around a 10% or more reduction in growth.

16 weeks: No new tumor growth. Again there was a slight reduction in some tumors, including those in my brain although the effect was not as pronounced as before.

32 weeks: Again there was no new tumor growth. Again there was a slight reduction in some tumors, including those in my brain and once again the effect was not quite as pronounced as at 16 weeks.

I am still on the trial and below I have listed the side effects I have been dealing with. Here it is worth noting that I have managed to stay on the full 45mg dose of this drug, I am fortunate as everyone else on the trial has had to have their dose reduced to 30mg as some or all of the side effects have been too much. I will only list what I have had to deal with, a full list of side effects can easily be found with a rudimentary google search.

SIDE EFFECTS: Side effects for me have included (from most prominent to least), diarrhoea (this is common, happens to me a lot throughout the day and night and is accompanied by sometimes quite painful stomach cramps), sore throat (again common, this is often accompanied by a hoarse voice, which can be sexy or so I'm told, and has meant for other patients they have unfortunately had problems with eating their food), problems eating spicy foods (although by no means a serious problem your taste buds on your tongue enlarge, spicy foods and anything hot in temperature are problems), tiredness (this effects more sometimes than others and means I sleep a lot occasionally, nothing new there then!).
In terms of side effects this is it for me, I am lucky. Others have had more problems.

I think this is all the details I have for the moment regarding this trial. I will post new information up here when I get it and keep you all informed the progress. I wish everyone well and if anyone would like ANY information on this or anything else please feel free to e-mail me at: mavs_1357@hotmail.com

All the best everyone, lots of love, Paul X