Tissue macrophages: heterogeneity and functions

[D.ap]

Tissue macrophages: heterogeneity and functions

Abstract
Macrophages are present in all vertebrate tissues, from mid-gestation throughout life, constituting a widely dispersed organ system. They promote homeostasis by responding to internal and external changes within the body, not only as phagocytes in defence against microbes and in clearance of dead and senescent cells, but also through trophic, regulatory and repair functions. In this review, we describe macrophage phenotypic heterogeneity in different tissue environments, drawing particular attention to organ-specific functions.

https://bmcbiol.biomedcentral.com/artic ... 017-0392-4

[D.ap]

https://bmcbiol.biomedcentral.com/artic ... 017-0392-4

Listen to pronunciation. (MA-kroh-fayj) A type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cell