Case Report Alveolar Soft Part Sarcoma with Unusual Cardiac Metastasis: A Case Report and Review of the Literature
Re: Case Report Alveolar Soft Part Sarcoma with Unusual Cardiac Metastasis: A Case Report and Review of the Literature
Abstract
Alveolar soft part sarcoma is a very uncommon soft tissue malignancy which accounts for <1% of soft tissue sarcoma. It is a malignant and highly vascular tumor arising most commonly in the musculature of the lower extremities, with metastasis primarily to the lungs, bones, and brain. Cardiac metastasis is very rare and only 5 cases have been reported in the literature so far. We report a case of a young woman with a history of surgically resected alveolar soft part sarcoma of left thigh who presented with persistent dry cough and was found to have a cardiac mass, which on biopsy proved to be alveolar soft part sarcoma.
1. Introduction
Alveolar soft part sarcoma (ASPS) is a rare soft tissue neoplasm that accounts for less than 1% of all soft tissue sarcomas [1] and affects individuals between 15 and 35 years of age primarily, with a slight female preponderance [2]. In adults, the most common site is the deep soft tissues in the thigh or buttock. However, it is known to occur in organs such as lungs, breasts, stomach, female genital organs, and bones [3, 4]. It is a malignant and highly vascular tumor, and metastases to the lungs, bones, and brain are common while cardiac metastasis is extremely rarely [5, 6]. We report a case of a young woman who had history of ASPS of the left thigh which was resected. She presented one year later with a dry cough and was found to have a cardiac mass, which on biopsy was consistent with ASPS.
Alveolar soft part sarcoma is a very uncommon soft tissue malignancy which accounts for <1% of soft tissue sarcoma. It is a malignant and highly vascular tumor arising most commonly in the musculature of the lower extremities, with metastasis primarily to the lungs, bones, and brain. Cardiac metastasis is very rare and only 5 cases have been reported in the literature so far. We report a case of a young woman with a history of surgically resected alveolar soft part sarcoma of left thigh who presented with persistent dry cough and was found to have a cardiac mass, which on biopsy proved to be alveolar soft part sarcoma.
1. Introduction
Alveolar soft part sarcoma (ASPS) is a rare soft tissue neoplasm that accounts for less than 1% of all soft tissue sarcomas [1] and affects individuals between 15 and 35 years of age primarily, with a slight female preponderance [2]. In adults, the most common site is the deep soft tissues in the thigh or buttock. However, it is known to occur in organs such as lungs, breasts, stomach, female genital organs, and bones [3, 4]. It is a malignant and highly vascular tumor, and metastases to the lungs, bones, and brain are common while cardiac metastasis is extremely rarely [5, 6]. We report a case of a young woman who had history of ASPS of the left thigh which was resected. She presented one year later with a dry cough and was found to have a cardiac mass, which on biopsy was consistent with ASPS.
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