AACR Pipeline Drugs - Some ASPS data Cediranib, Foretinib
Posted: Mon Nov 23, 2009 6:38 pm
Came across the abstracts:
http://www.modernmedicine.com/modernmed ... ryId=40159
3 abstractions mention ASPS by name:
A4: Avastin and Cediranib - one ASPS patient had a partial response RECIST of 24%
A5: Dosing trial of Cediranib in kids - similar side effect profile as adults, better if lower dose titrated up rather than starting high.
A78 Foretinib: Oral met inhibitor + VEGFR2 inhibitor. ASPS was 'event-free' at 12 months (I think that means stable).
http://www.modernmedicine.com/modernmed ... ryId=40159
3 abstractions mention ASPS by name:
A4: Avastin and Cediranib - one ASPS patient had a partial response RECIST of 24%
A5: Dosing trial of Cediranib in kids - similar side effect profile as adults, better if lower dose titrated up rather than starting high.
A78 Foretinib: Oral met inhibitor + VEGFR2 inhibitor. ASPS was 'event-free' at 12 months (I think that means stable).