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Washout period before going on another TKI

Posted: Wed Dec 08, 2010 12:09 pm
by Arch
According to a study in RCC, patients who switched to sutent from another VEGF inhibitor responded better if there was atleast a 30 days washout period.
Thought of sharing this as many people here are trying different VEGF inhibitors sequentially. I thought it was best if there was no gap, so that no rebound occurs, but this study states otherwise.
Look at this -
http://www.asco.org/ascov2/Meetings/Abs ... ctID=20118

Re: Washout period before going on another TKI

Posted: Wed Dec 08, 2010 4:27 pm
by Olga
And accidentally it is the time that most trials usually require to have after the previous TKI or chemo treatment...