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Vitamin D Deficiency May Promote Spread of Some Breast Cancers
Posted: Fri Nov 08, 2019 9:21 pm
by D.ap
The findings from this study aside, maintaining normal levels of vitamin D is important for women with breast cancer, Dr. Feldman stressed.
Women over 60 are at increased risk for osteoporosis and the therapies used to treat breast cancer make this risk even greater,” he said. “Having normal vitamin D levels is especially important for women with breast cancer to optimize bone heath independent from the potential effects on the tumor we identified.
Vitamin D may prolong life in people with cancer
Posted: Fri Nov 08, 2019 9:30 pm
by D.ap
Taking vitamin D can prolong life in people who develop cancer, according to a recent analysis of clinical trials.
Researchers at Michigan State University (MSU) in East Lansing analyzed data from randomized controlled trials that had compared people who took vitamin D supplements with those who took a placebo for at least 3 years.
They only included trials that had examined the use of vitamin D supplements to prevent disease over a minimum follow-up of 4 years and had also recorded the incidence of cancer and cancer-related deaths.
In all, the analysis took in 10 trials with a total of 79,055 participants. Their average age was 68 years, and 78% of them were female.
The team found a significant link between the use of vitamin D supplements and a lower risk of death to cancer over the follow-up period.
The analysis showed that people who took vitamin D supplements had a 13% lower risk of dying from cancer than those who took a placebo over the same period.
There was no significant association, however, between vitamin D use and prevention of cancer.
https://www.google.com/amp/s/www.medica ... amp/325417
Role of vitamin D supplementation for primary prevention of cancer:
Posted: Fri Nov 08, 2019 9:32 pm
by D.ap
1534
Background: In the United States cancer is the second leading cause of mortality, as such, primary prevention of cancer is a major public health concern. Vitamin D supplementation has been studied as a primary prevention method for multiple diseases including cardiovascular disease, osteoporosis, diabetes mellitus and cancer. The role of aspirin as primary prevention of cancer is still controversial. With fast emergence of large randomized controlled trials (RCTs) in that regards, we aimed to evaluate the efficacy of Vitamin D supplementation as primary prophylaxis for cancer. Methods: A comprehensive electronic database search was conducted for all RCTs where comparison of Vitamin D supplementation versus placebo for the prevention of any type of disease with at least 3 years of Vitamin D supplementation was used and where cancer incidence or mortality was reported. The primary outcome was cancer-related mortality and cancer incidence. We calculated risk ratios (RRs) and 95% confidence intervals (CIs) using a random-effects model at the longest follow-up. Results: We included 10 RCTs with 79,055 total patients, mean age of 68.07 years, a female percentage of 78.02% and a minimum follow-up of 4 years and more. Vitamin D was associated with significant reduction of cancer-related mortality compared with placebo (RR 0.87; 95% CI: 0.79-0.96; P = 0.05: I2= 0%). Compared with placebo, Vitamin D was not associated with significant reduction of cancer incidence (RR: 0.96; 95% CI: 0.86-1.07; P = 0.46; I2= 31%). Conclusions: Our study highlights that the use of Vitamin D supplementation for primary prevention of cancer is important as it does decrease cancer-related mortality once cancer is diagnosed, however it has no role or effect on cancer incidence.
https://ascopubs.org/doi/10.1200/JCO.20 ... suppl.1534
Re: Vitamin D Deficiency May Promote Spread of Some Breast Cancers
Posted: Sat Nov 09, 2019 1:25 pm
by Olga
Ivan takes the Vit D every day. Vit D levels can be measured. Some people even have the genetic polymorphism when the vit D is not metabolized properly.