red alert article for anyone on immunotherapy trials/treatments

[Olga]

Deb shared with me this immune therapy blog (Dr. Breelyn Wilky twitted this from Science Times newsletter).
It is a very important review of the acute side effects caused by the overreacting/overstimulated immune system attacking the person's organs leading to acute diabetes and multi organ failure. With the number of the clinical trials and more important off label use of these drugs - tageted immune therapy - expanding rapidly and not enough funding from the companies producing these amazingly expensive drugs directed toward studying and documenting the acute and chronic side effects - the situation became very alarming and the patients have to be widely aware of the newly discovered side effects.
Pleas read it if you are on the clinical trial or taking the drug off label.

https://cdn.ampproject.org/c/s/mobile.n ... r.amp.html
or
http://tinyurl.com/z3wxj5a

with any of the worrying side effects signs please discontinue the drug immediately, go to ER and ask them to contact the oncologist. Steroids are found to help in some cases.

[Olga]

There is an additional info on the subject going back found by Deb - it is going back as early as 2008 - pub Med article and it points out what has been the possible side effects since the beginning of using immune therapies for cancer (Autoimmune related).

Immunotherapy of autoimmunity and cancer: the penalty for success

https://www.ncbi.nlm.nih.gov/pmc/articl ... o=0.793651
PMCID: PMC2764117