Why does cancer affect men and women differently?

[D.ap]

“Men and women are different in many ways, from the organs in their bodies to the emotions they wear on their sleeves, even in how they approach an argument or take on a task. So it may come as little surprise that cancer—a disease influenced by genetics, biology and lifestyle habits—affects men and women differently, too. The question that still stumps scientists is: Why?”




https://www.cancercenter.com/discussion ... fferently/




Historically, men are more likely to get cancer and women are more likely to survive it. The evidence is backed by numerous statistics—chief among them the American Cancer Society’s (ACS) estimate that nearly one in two men will be diagnosed with cancer in his lifetime, compared with one in three women. While the statistics are straightforward, the causes behind the disparity have been harder to explain. “Some things affect gender differently,” says Dr. Ricardo Alvarez, Director of Cancer Research and Breast Medical Oncologist at our hospital near Atlanta. “We know that. What can we do with that, though?” Several studies in the past few years have identified some promising leads that may one day answer that question.

[D.ap]

Asps
More females to males

A possible explanation-



BACKGROUND

Alveolar soft‐part sarcoma (ASPS) is a rare malignant soft tissue tumor with both clinically and morphologically distinct features. It often involves the extremities of adolescents and young adults and shows a predilection for females. Recently, ASPS was found to have a nonreciprocal der(17)t(X;17) translocation with the corresponding fusion gene located in chromosome 17. Because females have an extra X‐chromosome, their likelihood of developing an X;autosome translocation is theoretically double that of males, and thus, this extra X‐chromosome is a likely explanation for female predominance of ASPS.


https://onlinelibrary.wiley.com/doi/ful ... cncr.20899

[D.ap]

So I’d hope that ASPS is being looked at from a different perspective , as it should .

Metabolically , hormonally and environmentally .
From young kids (female ) to young males and females, to pregnant women, as well as lifestyle choices, these are all to be considered , when treating ASPS.