CRISPR could deliver a certain cure in the next 5-10 years

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Ivan
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CRISPR could deliver a certain cure in the next 5-10 years

Post by Ivan »

As some of you may know, I've been very skeptical of anything that has promised any sort of "cure" rather than treatment for ASPS. However, I am really excited about this - http://www.bloomberg.com/news/articles/ ... man-trials

I first learned about this last year from a good friend of mine who uses it in her neuroscience research. This is not pie in the sky empty promise stuff that is like 99.9999% of things that promise a cure for cancer. This is an actual technology that is widely and successfully used currently that is starting human trials within 12 months. CRISPR can cure our disease permanently. We just need to hold out for it to be developed and brought to market, which will take around 5 years.

When this first goes public, it will cost money and it won't be covered by your insurance just yet. Start saving $100K just to be sure you can afford it.

We'll be able to get new organs too, for those of us who have lost and or damaged something during the course of previous treatment. This is all coming, and soon enough. Your only job is to make sure that you can afford it.

At this point point, we are almost past the point of hoping for a cure. It's almost a waiting game now.

This describes the mechanism (source: http://gizmodo.com/everything-you-need- ... 1702114381)
As the CRISPR region fills with virus DNA, it becomes a molecular most-wanted gallery, representing the enemies the microbe has encountered. The microbe can then use this viral DNA to turn Cas enzymes into precision-guided weapons. The microbe copies the genetic material in each spacer into an RNA molecule. Cas enzymes then take up one of the RNA molecules and cradle it. Together, the viral RNA and the Cas enzymes drift through the cell. If they encounter genetic material from a virus that matches the CRISPR RNA, the RNA latches on tightly. The Cas enzymes then chop the DNA in two, preventing the virus from replicating.
Substitute 'microbe' above for 'your body' and 'virus' for 'asps' -> cured.
As this point, you can start connecting the dots: Cas9 is an enzyme that snips DNA, and CRISPR is a collection of DNA sequences that tells Cas9 exactly where to snip. All biologists have to do is feed Cas9 the right sequence, called a guide RNA, and boom, you can cut and paste bits of DNA sequence into the genome wherever you want.

youtu.be/2pp17E4E-O8
D.ap
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Re: CRISPR could deliver a certain cure in the next 5-10 years

Post by D.ap »

Ivan
Looks pretty amazing !
Looks like NIH has approved clinical trials


http://time.com/4380352/crispr-human-trial-us/
Debbie
MartinBube
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Re: CRISPR could deliver a certain cure in the next 5-10 years

Post by MartinBube »

I really hope that this is going to change a lot for the people fighting cancer
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