Alveolar soft part sarcoma with brain metastases

[D.ap]

Asian J Neurosurg. 2017 Jan-Mar; 12(1): 112–115.
doi: 10.4103/1793-5482.144197
PMCID: PMC5379782

Abstract
Metastatic tumors are the most common mass lesions in the brain. This case reports a rare form of sarcoma with metastasis to the brain. The appropriate management of a patient with metastatic alveolar soft part sarcoma to the brain is discussed. Author describes a 32-year-old gentleman diagnosed with primary tumor at gluteus and distant metastases at lower lobe of right lung and the brain. Histopathology proves diagnosis as alveolar soft part sarcoma. Craniotomy with excision of brain lesion was done. Repeated magnetic resonance imaging of the brain after 2 months showed rapidly growing new lesions. The next step of management was made by the oncology team as recurrence rate was high and due to multi-systemic involvement. Patient was planned for palliative chemotherapy and to be reassessed later. This case report discusses the appropriate approach to any form of brain metastases and the role of early follow-up especially after surgery for better outcome and choice of post operative management such as radiotherapy or chemotherapy or both for malignant tumors. Based on this report, it was concluded that every brain tumor patient should be frequently monitored even in the outpatient setting as most of them are metastatic and rapidly spreading. The patient should be considered for radiotherapy or chemotherapy or both after surgery if the histopathology result is suggestive of malignancy.


https://www.ncbi.nlm.nih.gov/pmc/articl ... po=32.7586

[D.ap]

What has been discovered to be the best treatment for ASPS brain mets, posted by Jussi


http://www.cureasps.org/forum/viewtopic.php?f=8&t=1443

[Olga]

It took a very considerable effort to find and then to actually have been treated by this amazing radiosurgery doctor from China thanks to our Chinese members and Jussi and his father persistence. I would not expect that anyone in US/Canada or elsewhere would agree to treat such a high number - very multiple brain mets - perhaps more than 10 brain mets would be a cut off - hard to say? - by the GammaKnife.