Possible association between tumor-suppressor gene mutations and hMSH2/hMLH1 inactivation in alveolar soft part sarcoma

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Written in 2003 of microsatellite instability in a group of ASPS patients .

Furthermore, microsatellite instability (MSI) analysis and loss of heterozygosity (LOH) on chromosome 5q analysis were used for some cases of ASPS where DNA derived from normal tissue was available

https://www.ncbi.nlm.nih.gov/m/pubmed/14562278/

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Johannes mentioned in a conversation back in feb of 2016

"MSI-high would have been needed to get into this Pembrolizumab trial: https://clinicaltrials.gov/ct2/show/NCT ... bec&rank=7 (one of the inclusion criteria "for any other advanced solid tumor" being that it is Microsatellite Instability (MSI)-High)."

Granted the trial is predominately cancer patients
http://www.cureasps.org/forum/viewtopic ... lity#p9002.