New Therapeutic Targets in Alveolar Soft Part Sarcoma Described in a New Publication
New Therapeutic Targets in Alveolar Soft Part Sarcoma were revealed in a new study conducted by Dr. Ewa Sicinska from the Department of Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, and Dr. Matt Hemming from the Department of Medicine, Division of Hematology and Oncology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA. […]
Summer 2022: Updated Clinical Research on Alveolar Soft Part Sarcoma
Below are links to eighteen publications describing clinical studies of ASPS with novel treatments as well as preclinical information on ASPS. The ASPS community is thankful to all the Principle Investigators, Oncologists and Researchers who are working with us to find a cure for ASPS! Anlotinib with Toripalimab for ASPS Therapy Complete Response of Metastatic […]
2019 Progress Report on Alveolar Soft Part Sarcoma – American Society of Clinical Oncology (ASCO) annual meeting
We selected to highlight 3 studies that were presented this year at the ASCO conference: 1. Treatment of ASPS with anlotinib (a new oral tyrosine kinase inhibitor therapy), Clinical trial information: NCT02449343 2. Combination treatment of ASPS with NKTR214 (immune modulator) and nivolumab (immune checkpoint inhibitor), Clinical trial information: NCT03282344 3. Successful generation of patient-derived xenografts and cell […]
Update on Alveolar Soft Part Sarcoma Clinical and Preclinical Studies as Presented at the Annual Meeting of CTOS in November 8-11, 2017
Below are summaries of three clinical studies and one preclinical study on Alveolar Soft Part Sarcoma as were presented at the 2017 annual meeting of the “Connective Tissue Oncology Society” (CTOS) in November 8-11. Please click the titles of each one of the 3 clinical studies to read more information on the “clinical Trials.gov” website. […]
Alveolar Soft Part Sarcoma Tumor Metabolizes Lactate by Goodwin and Jin et al in “Cancer Cell” Journal
Cancer Cell 26, 851-862, December 8,2014 The research from the group of Dr. Kevin Jones from the university of Utah was published in December 2014. It gives very important information on the metabolism of ASPS. It demonstrates that lactate drives proliferation of ASPS. The full paper is available here. The researchers initiated the study by creating […]
Research on ASPS presented at the conference of the “American College of Medical Genetics”
Dr. Shamini Selvarajah presented a summary of her studies on Alveolar Soft Part Sarcoma at the 2011 ACMG Annual Clinical Genetics Meeting that took place at the Vancouver Convention Center, Vancouver, BC, Canada. Dr. Selvarajah is one of the dedicated scientists from the Dana Farber Cancer Institute in Boston. They study ASPS relentlessly, aiming to […]
Tumor Expression Profile of Alveolar Soft Part Sarcoma May Pave the Way for New Treatments at The Dana Farber Cancer Institute
Scientists from the group of Dr. Massimo Loda reported the results of an extensive study that aims to identify potential therapeutic targets for ASPS last Friday. The research team, comprised of Shamini Selvarajah (PhD), Eleanor Chen (MD, PhD), and Saumyadipta Pyne (PhD), used cDNA microarray technology (gene expression array) to examine the expression of 18,401 […]
Potential Therapeutic Targets in Alveolar Soft Part Sarcoma – by Dr. Dina Lev
Dr. Dina Lev, from the Cancer Biology and the Sarcoma Research Center at the University of Texas M. D. Anderson has published a new study on Alveolar Soft Part Sarcoma. Her study appeared in the Journal of Histopathology. The aim of this study was to evaluate the expression of potential gene therapeutic targets in a cohort of […]
Establishment of the first Alveolar Soft Part Sarcoma cell line by Dr. Vistica and other researchers from the National Cancer Institute, Bethesda, MD
A poster presented last month at the 2009 American Association for Cancer Research (AACR) Annual Meeting in Denver, CO, announced a breakthrough in research that aims to find a cure for ASPS. For the first time, a team of researchers, among them Dr. David Vistica, reported their success in the establishment of a stable Alveolar […]
Gene Expression Profiling of Alveolar Soft-Part Sarcoma (ASPS)
Dr. David Vistica, and his collaborators from the National Cancer Institute (in Frederick, MD), published the results from their analysis of gene expression in donated ASPS tumors. It identified elevated expression of genes, related to cancer. These may have diagnostic and therapeutic potential. Few examples are: Involved in angiogenesis: ANGPTL2, HIF-1 alpha, MDK, c-MET, VEGF, […]