Event Summary: The second Annual Knockin’ Down ASPS Event in the memory of Anthony Salisbury (AJ)
The second Annual Knockin’ Down ASPS Event in the memory of Anthony Salisbury (AJ) took place on April 10th, 2010. Over $16,000 were raised this year, which were donated directly to the laboratory of Dr. Glenn Dranoff at the Dana Farber Cancer Institute in Boston in favor of his efforts of finding a cure for […]
Minimally Invasive Procedures for Tumor Ablation
For Alveolar Soft Part Sarcoms patients the use of aggressive surgery, appropriate diagnostic imaging, and long-term surveillance for metastases are critical to achieve long-term survival (Kayton et al 2006). When surgery is not possible, then local treatment like tumor ablation may be considered. In the past we discussed the benefits of Stereotactic Radiosurgery (SRS). There are different […]
Potential Therapeutic Targets in Alveolar Soft Part Sarcoma – by Dr. Dina Lev
Dr. Dina Lev, from the Cancer Biology and the Sarcoma Research Center at the University of Texas M. D. Anderson has published a new study on Alveolar Soft Part Sarcoma. Her study appeared in the Journal of Histopathology. The aim of this study was to evaluate the expression of potential gene therapeutic targets in a cohort of […]
Cediranib (AZD2171): Phase II Study in Patients With Alveolar Soft Part Sarcoma
Cediranib (Recentin, AZD2171) is an inhibitor of VEGF (Vascular Endothelial Growth Factor) receptors. Therefore, the drug inhibits angiogenesis: the formation of new blood vessels. Angiogenesis, in the context of cancer, enables blood supply to tumors, resulting in tumor growth and spread. Cediranib is being developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral […]
Support Team ASPS in the 2009 Pan-Massachusetts Challenge (PMC)
This weekend, Team ASPS rode the Pan-Massachusetts Challenge (PMC) for the 6th time. This bike-a-thon crosses Massachusetts to raise money for cancer research and clinical trials at the Dana-Farber Cancer Institute in Boston. Donations raised by Team ASPS are restricted for research and clinical trials that aim to find cure for Alveolar Soft Part Sarcoma. […]
Fundraiser in the memory of Anthony Salisbury (AJ)
On 26 January 2009, we lost Anthony Salisbury (AJ) to ASPS. AJ’s fiancé, family and friends remain committed to finding a cure for ASPS. In February 2009 they organized the“Knockin’ Down ASPS†event. During this fundraiser they collected over $19,000. Of that money, $3,000 went to AJ’s family, and $16,000 were donated to the laboratory […]
Establishment of the first Alveolar Soft Part Sarcoma cell line by Dr. Vistica and other researchers from the National Cancer Institute, Bethesda, MD
A poster presented last month at the 2009 American Association for Cancer Research (AACR) Annual Meeting in Denver, CO, announced a breakthrough in research that aims to find a cure for ASPS. For the first time, a team of researchers, among them Dr. David Vistica, reported their success in the establishment of a stable Alveolar […]
Gene Expression Profiling of Alveolar Soft-Part Sarcoma (ASPS)
Dr. David Vistica, and his collaborators from the National Cancer Institute (in Frederick, MD), published the results from their analysis of gene expression in donated ASPS tumors. It identified elevated expression of genes, related to cancer. These may have diagnostic and therapeutic potential. Few examples are: Involved in angiogenesis: ANGPTL2, HIF-1 alpha, MDK, c-MET, VEGF, […]
Team ASPS and Team AVEO Combine Efforts in the 2008 PMC to Raise Funds for ASPS Cure
The PMC is a bike-a-thon that crosses Massachusetts to raise money for cancer research and treatment at the Dana-Farber Cancer Institute (DFCI) in Boston. In August 2008, Team AVEO joined Team ASPS in our efforts to collect funds for finding a cure for ASPS. All of the funds raised by Team ASPS go directly to […]
iCureASPS Continues to Support ASPS Research in the Laboratory of Dr. Dina Lev at MD Anderson Cancer Center, TX
In April 2008, iCureASPS started to support the research of Dr. Dina Lev, MD, on Alveolar Soft Part Sarcoma. Dr. Dina Lev is Assistant Professor at the Sarcoma Research Center, MD Anderson Cancer Center, Houston Texas. In November 2008, iCureASPSÂ donated an additional $5,000 to her laboratory. Dr. Lev published a study on angiogenesis-promoting genes in […]