1. Phase II Study of Sorafenib in Patients With Advanced Soft Tissue Sarcomas

2. Sorafenib in Treating Patients With Soft Tissue Sarcomas

Alveolar Soft Part Sarcoma (ASPS) is highly angiogenic: it involves intensive growth of new blood vessels into the tumor. Those blood vessels connect the tumor to the blood system, supply oxygen and nutrients to the tumor, remove waste and enable dissemination of tumor cells into the body through this connection to the blood stream. Therefore, it is possible that the application of specific drugs, which may inhibit the creation of new blood vessels, is a way to combat ASPS.

Sorafenib (Nexavar) is designed to interfere with growth of new blood vessels and the growth of new cancer cells.

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Yosef Landesman, Ph.D.
President & Cancer Research Director
Cure Alveolar Soft Part Sarcoma International (iCureASPS)
e-mail: mailto:landesmany@yahoo.com