Rheumatic Diseases and Malignancies

[D.ap]

ABSTRACT
There are many studies which demonstrate a higher risk for malignancy in patients with rheumatic diseases. There have been a number of possible explanations for the differences in the risk of certain malignancies in patients with rheumatic disease, compared with general population, but a clear mechanism is difficult to identify.

Rheumatoid syndromes may be associated with malignancy as paraneoplastic conditions, which can antedate the neoplasm diagnosis.

On the other hand, autoimmune rheumatic diseases have a higher risk of malignancy by themselves or because of the immunosuppressant treatments.

Keywords: rheumatic disease, malignancy, paraneoplastic syndromes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593292/